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New Discovery Can Help Target Pediatric Brain Tumor Therapies

By Kayla Giacin
Tuesday, April 2, 2013

There is new and promising news in research of pediatric brain tumors.  Currently, brain tumors are treated with medications, surgery, radiation, chemotherapy or a combination of any of these therapies.

While these can be effective at decreasing or eliminating tumors, as many of you know these treatments come at a cost.  Physical, cognitive, and emotional changes are common among brain tumor survivors and since no two tumors are completely alike, each one may respond differently to these treatments with varied results.

Children’s Hospital of Philadelphia (CHOP) has announced that their research project, the Childhood Brain Tumor Tissue Consortium, which is being supported by the Children’s Brain Tumor Foundation, has begun to look at an exciting new discovery that looks at how the BRAF gene, a mutated gene thought to cause human cancers, may mutate in different ways that result in a particular tumor or cancer type.  The goal of this study is to use gene-sequencing data to see what this means for pediatric brain tumors and how it influences what type of tumor will result from a particular mutated gene.

This means that if these mutations can be followed and defined, therapies can begin to target specific tumor types instead of generalized therapy, resulting in more effective treatments with the possibility of causing less damage to surrounding healthy tissue.

CBTF is excited to be providing critical financial support that made this study possible. This support results from the generous sponsorship offered by the members of the Licensing Industry Merchandisers’ Association (LIMA).

For more information about this study, please visit:  

http://www.chop.edu/news/gene-pathways-suggest-drugs-for-childrens-brain-tumors.html

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